BIOL& 260 Microbiology • 6 Cr.
Explores structure, function, and taxonomy of microbes, including bacteria and viruses, and their relationships to health and disease. Format includes substantial laboratory work and written reporting. Prerequisite: BIOL& 160 or BIOL& 211 with a C or better, or entry code.
After completing this class, students should be able to:
- Explain the current hypothesizes regarding the origin of the first cellular life.
- Describe the role microbes play in the environment.
- Identify the scientists relevant to microbiology and describe the contributions they have made to the discipline.
- Describe the contribution of Carolus Linnaeus and Carl Woese to classification and identify the criteria used to determine cell type, domain, Prokaryotic (bacteria and Archaea) divisions and groups.
- Describe viral, Prokaryotic, viroid and prion structure and reproduction.
- Describe microbial genetics: Structural and functional organization of nucleic acids from nucleoside to genome, DNA replication, transcription, translation, and control of gene expression.
- Apply microbial genetics and genetic engineering to understanding biotechnology today.
- Describe the sources of genetic variation: mutations, transposons, conjugation, transduction and transformation.
- Explain the difference between vertical and lateral gene transfer and give examples of each.
- Compare Prokaryotic metabolism (fermentation, cellular respiration, chemosynthesis and photosynthesis) with metabolism in Eukarya.
- List the elements of microbial nutrition, and growth.
- List and describe the major physical and chemical controls of microbial growth and reproduction.
- Explain immunity, both innate and acquired.
- Identify the pathogenic strategies used by microbes.
- Describe phases of infection and types of infection.
- Distinguish between, epidemic, pandemic and endemic diseases.
- Describe the phases of an epidemic.
- Explain the medical importance of bacteria, viruses, protozoa, fungi, prions and viroids in causing infectious human diseases. Compare and contrast the major microbial diseases presented by your instructor.
- Identify the major prevention (sanitation, vaccines) and treatment (antibiotics and antivirals) strategies used to help a human host maintain a balance between health and disease.
- Identify and describe the main themes of microbiology today, e.g. increase in virulence, re-emerging diseases, emerging diseases, and antibiotic resistance
- Demonstrate general laboratory techniques of an introductory microbiology lab (e.g. microscope use, staining and use of the appropriate media and biochemical tests to grow and identify microorganisms).
- Develop the general conceptual skills (e.g. observation, problem solving, hypothesis generation, and testing) that are used in the life sciences.
- Demonstrate laboratory safety while using basic laboratory equipment, e.g. aseptic technique.
- Demonstrate the ability to read instructions and follow their directives.