CHEM& 262 Organic Chemistry II • 6 Cr.
Second in a three-course organic chemistry sequence. Format includes laboratory work. Prerequisite: CHEM& 261.
After completing this class, students should be able to:
- Name (including E/Z) and list typical properties of ordinary alkenes
- Devise synthetic pathway to produce Hoffman and Zaitsev alkenes
- Predict basic reactions of alkenes, esp. in regard to Markovinkov’s rule
- Write the mechanism for ordinary alkene reactions
- Calculate the index of hydrogen deficiency in alkenes and alkynes
- Name and list typical properties of ordinary alkynes
- Devise synthetic pathways to produce most alkynes
- Predict basic reactions of alkynes
- Write mechanisms for ordinary alkyne reactions.
- NMR Spectroscopy
- Explain chemical shift, intergration, and splitting patterns
- Deduce structures or predict NMR spectra of typical organic molecules.
- Identify irregular splitting patterns with alkenes, aromatics, an diastereotopic hydrogens
- Determine which atomic nuclei can be visible to NMR
- Explain (on an elementary level) how NMR spectra are obtained
- Explain how NMR samples must be prepared
- Alcohols and Ethers
- Name and list typical properties of ordinary alcohols and ethers
- Devise synthetic pathways to produce most alcohols and ethers
- Predict basic reactions of alcohols and ethers
- Write mechanisms for ordinary alcohol and ether reactions
- Conjugated Unsaturated Systems
- Identify, explain, and predict stability of conjugated systems
- Summarize and explain the rules of resonance structures
- Apply resonance theory to explain thermodynamic and kinetic outcomes of appropriate reactions.
- Identify aromatic, anti-aromatic, pseudo-aromatic, and non-aromatic compounds, including hetero-cycles
- Name aromatic compounds
- Devise synthetic pathways for aromatic compounds
- Predict basic reactions of aromatics
- Write mechanisms for ordinary aromatic reactions
- Apply aliphatic reaction principles to aromatic side chain reactions
- Explain the unusual stability of benzene and list the reactions that result in its ultimate reduction