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CHEM& 263 Organic Chemistry III • 6 Cr.

Department

Division

Description:

Third in a three-course sequence. Continues the lecture and lab component of CHEM& 261 and CHEM& 262. Topics include functional groups and biologically important compounds. Format includes laboratory work. Prerequisite: CHEM& 262.

Outcomes:

After completing this class, students should be able to:

  • Aldehydes and Ketones
    • Name and list typical properties of ordinary aldehydes and ketones
    • Devise synthetic pathways to produce aldehydes and ketones
    • List the differences in terms of reactivity between aldehydes and ketones
    • Predict basic reactions of aldehydes, ketones, and alpha-carbons
    • Write the mechanism for basic carbonyl reactions.
  • Carboxylic Acids and Derivatives
    • Name and list minimal properties of carboxylic acids, acid chlorides, acid anhydrides, esters, amides, and nitriles; list the relative reactivity of each
    • Devise synthetic pathways between derivatives and from other families.
    • Predict basic reactions of derivatives.
    • Write the mechanism for all derivative-to-derivative reactions
  • Dicarbonyls
    • Explain the acidity of alpha carbons
    • Predict the classic dicarbonyl reactions
  • Amines
    • Name and list typical properties of amines, including diazonium salts
    • Devise synthetic pathways to produce both aliphatic and aromatic amines
    • Predict basic amine reactions
    • Write the mechanisms of the Hoffman and Curtius rearrangements
  • Lipids and Amino Acids
    • Identify the major lipid families, giving properties of each
    • Identify isoprene units in typical terpenes and explain the mechanism of soap
    • Show the differences between cationic, anionic, and zwitterionic forms of amino acids, and the implications for gel electrophoresis
  • Proteins and Nucleic Acids
    • Explain transcription and replication, and how it relates to mutation.
    • Draw all possible DNA and RNA base pairs, including the phosphate backbone.
    • Explain the four levels of protein structure, and the intermolecular forces that determine them. Also explain denaturing, induced fit, and chaperoning.
    • Show how proteins are sequenced, and our current limitations
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Bellevue College
3000 Landerholm Circle SE Bellevue, WA 98007-6484 U.S.A.
Work: (425) 564-1000