RAIT 359 Basics of Positron Emission Tomography • 3 Cr.
Covers the basic science of positron emission tomography (PET) imaging, including the principles of coincidence imaging, the operation of a PET tomograph, and the creation and use of PET radiopharmaceuticals. Intended for individuals interested in pursuing clinical experience in PET. Prerequisite: RAIT 358 or certification as a nuclear medicine technologist.
After completing this class, students should be able to:
- Outline the basic concepts of positron emission tomography (PET), including coincidence imaging, types of events, need for attenuation correction, and time-of-flight.
- Identify the components of a PET tomograph and discuss its operation, including detector block and ring gantry design, corrections needed, reconstruction methods, quality control procedures, image acquisition, and artifacts.
- Describe the production of PET radionuclides in a cyclotron and in a generator and the manufacture of PET radiopharmaceuticals.
- Identify and discuss imaging procedures for commonly used PET radiopharmaceuticals, and briefly discuss the use of PET radiopharmaceuticals for research.
- Discuss in depth the physiology of fluorodeoxyglucose (FDG), including the need for careful patient preparation and normal variants; and identify and briefly discuss PET radiopharmaceuticals other than FDG.
- Briefly discuss 2D vs. 3D and time-of-flight imaging, dynamic image sequences, and gated imaging techniques.
- Describe performance measures used for PET tomographs and common artifacts in PET imaging.
- Discuss quantitative and semi-quantitative techniques in PET, particularly the standardized uptake value.
- Describe the benefits, acquisition techniques, and issues related to PET/CT, and briefly discuss PET/MR imaging.